ITT4608
ITT4608
- Catalog: ITT4608
- Gene/Protein: TESK2
- Product Description: Immunotag™ TESK2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TESK2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from TESK2, at AA range: 180-260 |
| Specificity | TESK2 Polyclonal Antibody detects endogenous levels of TESK2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TESK2 |
| Accession No. | Q96S53 Q8VCT9 Q924U5 |
| Alternate Names | TESK2; Dual specificity testis-specific protein kinase 2; Testicular protein kinase 2 |
| Description | testis-specific kinase 2(TESK2) Homo sapiens This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016], |
| Cell Pathway/ Category | Regulation of Microtubule Dynamics |
| Protein Expression | Brain,Testis, |
| Subcellular Localization | nucleus,nucleoplasm,cytoplasm, |
| Protein Function | Experimental confirmation may be lacking for some isoforms,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,cofactor:Manganese.,enzyme regulation:Activated by autophosphorylation on Ser-219.,function:Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Predominantly expressed in testis and prostate. Found predominantly in non-germinal Sertoli cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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