ITT4616
ITT4616
- Catalog: ITT4616
- Gene/Protein: GTF2E2
- Product Description: Immunotag™ TFIIE-β Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TFIIE-β |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TF2E2. AA range:151-200 |
| Specificity | TFIIE-β Polyclonal Antibody detects endogenous levels of TFIIE-β protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GTF2E2 |
| Accession No. | P29084 Q9D902 |
| Alternate Names | GTF2E2; TF2E2; Transcription initiation factor IIE subunit beta; TFIIE-beta; General transcription factor IIE subunit 2 |
| Description | function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.,similarity:Belongs to the TFIIE beta subunit family.,similarity:Contains 1 TFIIE beta DNA-binding domain.,subunit:Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H., |
| Cell Pathway/ Category | Basal transcription factors, |
| Protein Expression | Skin, |
| Subcellular Localization | nucleus,nucleoplasm,transcription factor TFIID complex,transcription factor TFIIE complex,cytoplasm, |
| Protein Function | function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.,similarity:Belongs to the TFIIE beta subunit family.,similarity:Contains 1 TFIIE beta DNA-binding domain.,subunit:Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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