ITT4692
ITT4692
- Catalog: ITT4692
- Gene/Protein: TNNI3K
- Product Description: Immunotag™ TNNI3K Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TNNI3K |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from TNNI3K, at AA range: 270-350 |
| Specificity | TNNI3K Polyclonal Antibody detects endogenous levels of TNNI3K protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TNNI3K |
| Accession No. | Q59H18 Q5GIG6 Q7TQP6 |
| Alternate Names | TNNI3K; CARK; Serine/threonine-protein kinase TNNI3K; Cardiac ankyrin repeat kinase; Cardiac troponin I-interacting kinase; TNNI3-interacting kinase |
| Description | TNNI3 interacting kinase(TNNI3K) Homo sapiens This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology. [provided by RefSeq, Sep 2012], |
| Cell Pathway/ Category | Fructose and mannose metabolism,Amino sugar and nucleotide sugar metabolism, |
| Protein Expression | Brain,Colon,Fetal kidney,Heart,Kidney,Stomach mucosa, |
| Subcellular Localization | nucleus,cytoplasm, |
| Protein Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,catalytic activity:GTP + beta-L-fucose 1-phosphate = diphosphate + GDP-L-fucose.,cofactor:Magnesium.,function:Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids.,function:May play a role in cardiac physiology.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 10 ANK repeats.,subcellular location:Expressed at lower levels in the cytoplasm.,subunit:Interacts with TNNI3, ACTC, ACTA1, MYBPC3, AIP, BABP3 and HADHB.,tissue specificity:Expressed in many tissues.,tissue specificity:Highly expressed in both adult and fetal heart., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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