ITT4732
ITT4732
- Catalog: ITT4732
- Gene/Protein: TRERF1
- Product Description: Immunotag™ TReP-132 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TReP-132 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TREF1. AA range:1071-1120 |
| Specificity | TReP-132 Polyclonal Antibody detects endogenous levels of TReP-132 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TRERF1 |
| Accession No. | Q96PN7 Q8BXJ2 |
| Alternate Names | TRERF1; BCAR2; RAPA; TREP132; Transcriptional-regulating factor 1; Breast cancer anti-estrogen resistance 2; Transcriptional-regulating protein 132; Zinc finger protein rapa; Zinc finger transcription factor TReP-132 |
| Description | transcriptional regulating factor 1(TRERF1) Homo sapiens This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014], |
| Protein Expression | Adrenal gland,Aorta,Epithelium,Placenta, |
| Subcellular Localization | histone deacetylase complex,nucleus,transcription factor complex, |
| Protein Function | function:Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.,similarity:Contains 1 ELM2 domain.,similarity:Contains 1 SANT domain.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with CREBBP and EP300.,tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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