ITT4750
ITT4750
- Catalog: ITT4750
- Gene/Protein: DCT
- Product Description: Immunotag™ TRP2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TRP2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DCT. AA range:51-100 |
| Specificity | TRP2 Polyclonal Antibody detects endogenous levels of TRP2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DCT |
| Accession No. | P40126 P29812 |
| Alternate Names | DCT; TYRP2; L-dopachrome tautomerase; DCT; DT; L-dopachrome Delta-isomerase; Tyrosinase-related protein 2; TRP-2; TRP2 |
| Description | catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex., |
| Cell Pathway/ Category | Tyrosine metabolism,Melanogenesis, |
| Protein Expression | Liver,Lymphnode melanoma metastases,Mammary gland,Melanoma, |
| Subcellular Localization | cytosol,integral component of membrane,melanosome membrane,melanosome, |
| Protein Function | catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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