ITT4758
ITT4758
- Catalog: ITT4758
- Gene/Protein: TSC22D1
- Product Description: Immunotag™ TSC-22 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TSC-22 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from TSC-22, at AA range: 40-120 |
| Specificity | TSC-22 Polyclonal Antibody detects endogenous levels of TSC-22 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TSC22D1 |
| Accession No. | Q15714 P62500 P62501 |
| Alternate Names | TSC22D1; KIAA1994; TGFB1I4; TSC22; hucep-2; TSC22 domain family protein 1; Cerebral protein 2; Regulatory protein TSC-22; TGFB-stimulated clone 22 homolog; Transforming growth factor beta-1-induced transcript 4 protein |
| Description | TSC22 domain family member 1(TSC22D1) Homo sapiens This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011], |
| Protein Expression | Brain,Brain cortex,Colon,Fetal brain,Kidney,Lung,Ovary,Testicle, |
| Subcellular Localization | nucleus,cytoplasm, |
| Protein Function | function:Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.,induction:In aortic endothelial cells, induced by cytokines, including TGFB.,similarity:Belongs to the TSC-22/Dip/Bun family.,subunit:Homodimer or heterodimer. Can form an heterodimer with TSC22D4.,tissue specificity:Widely expressed in fetal and adult tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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