ITT4825
ITT4825
- Catalog: ITT4825
- Gene/Protein: UCN
- Product Description: Immunotag™ Urocortin Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Urocortin |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Urocortin, at AA range: 40-120 |
| Specificity | Urocortin Polyclonal Antibody detects endogenous levels of Urocortin protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | UCN |
| Accession No. | P55089 P81615 P55090 |
| Alternate Names | UCN; Urocortin |
| Description | urocortin(UCN) Homo sapiens This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family. The encoded preproprotein is proteolytically processed to generate the mature peptide, an endogenous ligand for both corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. In the brain this peptide may be responsible for the effects of stress on appetite. This peptide may also play a role in mood disorders, neurodegeneration, and skeletal system disorders. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin-2. [provided by RefSeq, Feb 2016], |
| Protein Expression | Placenta, |
| Subcellular Localization | extracellular space,dendrite,varicosity,perikaryon,axon terminus, |
| Protein Function | function:Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF Receptor types 1, 2-alpha, and 2-beta.,similarity:Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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