ITT4846
ITT4846
- Catalog: ITT4846
- Gene/Protein: UTP14A
- Product Description: Immunotag™ UTP14A Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | UTP14A |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human UTP14A. AA range:321-370 |
Specificity | UTP14A Polyclonal Antibody detects endogenous levels of UTP14A protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | UTP14A |
Accession No. | Q9BVJ6 Q640M1 |
Alternate Names | UTP14A; SDCCAG16; U3 small nucleolar RNA-associated protein 14 homolog A; Antigen NY-CO-16; Serologically defined colon cancer antigen 16 |
Description | UTP14A small subunit processome component(UTP14A) Homo sapiens This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009], |
Protein Expression | Cervix,Epithelium,Eye,Muscle, |
Subcellular Localization | nucleoplasm,nucleolus,small-subunit processome, |
Protein Function | function:May be required for ribosome biogenesis.,miscellaneous:The human genome also contains the UTP14C gene, an autosomal retrotransposed copy of this X-linked gene. Evolution of autosomal retrogenes from X-linked progenitors compensates for X-chromosome silencing during male meiosis.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the UTP14 family.,tissue specificity:Ubiquitously expressed., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |