ITT4850
ITT4850
- Catalog: ITT4850
- Gene/Protein: VAMP1/VAMP2/VAMP3
- Product Description: Immunotag™ VAMP-1/2/3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | VAMP-1/2/3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human VAMP-1/2/3 |
| Specificity | VAMP-1/2/3 Polyclonal Antibody detects endogenous levels of VAMP-1/2/3 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | VAMP1/VAMP2/VAMP3 |
| Accession No. | P23763/P63027/Q15836 Q63666/P63045/P63025 |
| Alternate Names | VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP2; SYB2; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP3; SYB3; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptob |
| Description | vesicle associated membrane protein 1(VAMP1) Homo sapiens Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014], |
| Cell Pathway/ Category | SNARE interactions in vesicular transport, |
| Protein Expression | Brain,Skeletal muscle,Umbilical vein,Uterus, |
| Subcellular Localization | mitochondrial outer membrane,cytosol,integral component of plasma membrane,cell surface,integral component of membrane,cell junction,synaptic vesicle membrane,SNARE complex,azurophil granule membrane,specific granule membrane, |
| Protein Function | function:Involved in the targeting and/or fusion of transport vesicles to their target membrane.,similarity:Belongs to the synaptobrevin family.,similarity:Contains 1 v-SNARE coiled-coil homology domain.,subunit:Interacts with VAPA and VAPB.,tissue specificity:Nervous system, skeletal muscle and adipose tissue., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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