ITT4893
ITT4893
- Catalog: ITT4893
- Gene/Protein: VRK3
- Product Description: Immunotag™ VRK3 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | VRK3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from the Internal region of human VRK3. |
Specificity | VRK3 Polyclonal Antibody detects endogenous levels of VRK3 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | VRK3 |
Accession No. | Q8IV63 Q8K3G5 |
Alternate Names | VRK3; Inactive serine/threonine-protein kinase VRK3; Serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3 |
Description | vaccinia related kinase 3(VRK3) Homo sapiens This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008], |
Protein Expression | Brain,Liver,Skin,Testis,Trachea, |
Subcellular Localization | nucleus,cytoplasm, |
Protein Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Probable serine/threonine kinase.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.,similarity:Contains 1 protein kinase domain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |