ITT4947
ITT4947
- Catalog: ITT4947
- Gene/Protein: SLC39A1
- Product Description: Immunotag™ ZIP1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ZIP1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SLC39A1. AA range:111-160 |
| Specificity | ZIP1 Polyclonal Antibody detects endogenous levels of ZIP1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SLC39A1 |
| Accession No. | Q9NY26 Q9QZ03 |
| Alternate Names | SLC39A1; IRT1; ZIP1; ZIRTL; CGI-08; CGI-71; Zinc transporter ZIP1; Solute carrier family 39 member 1; Zinc-iron-regulated transporter-like; Zrt- and Irt-like protein 1; ZIP-1; hZIP1 |
| Description | solute carrier family 39 member 1(SLC39A1) Homo sapiens This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012], |
| Protein Expression | Kidney,Lung,Muscle,Placenta,Thyroid, |
| Subcellular Localization | endoplasmic reticulum membrane,plasma membrane,membrane,integral component of membrane, |
| Protein Function | function:Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells.,miscellaneous:Inhibited by Ni(2+) ions. Fe(2+) ions do not inhibit zinc uptake.,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,subcellular location:Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines.,tissue specificity:Ubiquitous. Expressed in most adult and fetal tissues including the epidermis., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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