ITT4948
ITT4948
- Catalog: ITT4948
- Gene/Protein: SLC39A2
- Product Description: Immunotag™ ZIP2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ZIP2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SLC39A2. AA range:11-60 |
| Specificity | ZIP2 Polyclonal Antibody detects endogenous levels of ZIP2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SLC39A2 |
| Accession No. | Q9NP94 |
| Alternate Names | SLC39A2; ZIP2; Zinc transporter ZIP2; 6A1; Eti-1; Solute carrier family 39 member 2; Zrt- and Irt-like protein 2; ZIP-2; hZIP2 |
| Description | solute carrier family 39 member 2(SLC39A2) Homo sapiens This gene encodes a member of the ZIP family of metal ion transporters. The encoded protein functions as a zinc transporter. Mutations in this gene may be associated with susceptibility to carotid artery disease. Multiple transcript variants have been described. [provided by RefSeq, Mar 2010], |
| Protein Expression | Prostate,Uterine ectocervix, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,cytoplasmic, membrane-bounded vesicle,cytoplasmic vesicle, |
| Protein Function | function:Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis.,induction:Shows a dramatic induction in normal epithelial cells contact inhibition.,miscellaneous:Zinc uptake is inhibited at pH levels below 7.0 and is stimulated at higher pH and is significantly inhibited by Cu(2+), Co(2+) and Mn(2+) ions. Not inhibited by Fe(2+).,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,tissue specificity:Expressed only in prostate and uterine epithelial cells., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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