ITT4989
ITT4989
- Catalog: ITT4989
- Gene/Protein: SLC30A4
- Product Description: Immunotag™ ZnT-4 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ZnT-4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from ZnT-4, at AA range: 40-120 |
| Specificity | ZnT-4 Polyclonal Antibody detects endogenous levels of ZnT-4 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SLC30A4 |
| Accession No. | O14863 O35149 O55174 |
| Alternate Names | SLC30A4; ZNT4; Zinc transporter 4; ZnT-4; Solute carrier family 30 member 4 |
| Description | solute carrier family 30 member 4(SLC30A4) Homo sapiens Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008], |
| Protein Expression | Fetal brain,Malignant prostate,Mesangial cell,Testis, |
| Subcellular Localization | cytoplasm,lysosomal membrane,late endosome,membrane,integral component of membrane,cytoplasmic, membrane-bounded vesicle,late endosome membrane, |
| Protein Function | domain:Contains a histidine-rich region which is a ligand for zinc and an aspartate-rich region which is a potential ligand for zinc.,function:Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment.,similarity:Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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