ITT5028
ITT5028
- Catalog: ITT5028
- Gene/Protein: EEA1
- Product Description: Immunotag™ EEA1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | EEA1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human EEA1. AA range:205-254 |
| Specificity | EEA1 Polyclonal Antibody detects endogenous levels of EEA1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | EEA1 |
| Accession No. | Q15075 Q8BL66 |
| Alternate Names | EEA1; ZFYVE2; Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2 |
| Description | disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding., |
| Cell Pathway/ Category | Endocytosis, |
| Protein Expression | Aorta,Cervix carcinoma,Fetal brain cortex,Skeletal muscle, |
| Subcellular Localization | cytoplasm,early endosome,cytosol,serine-pyruvate aminotransferase complex,membrane,extrinsic component of plasma membrane,cytoplasmic vesicle,early endosome membrane,axonal spine,recycling endosome,extracellular exosome,presynap |
| Protein Function | disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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