ITT5061
ITT5061
- Catalog: ITT5061
- Gene/Protein: BAG5
- Product Description: Immunotag™ BAGE5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | BAGE5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from BAGE5, at AA range: 30-110 |
| Specificity | BAGE5 Polyclonal Antibody detects endogenous levels of BAGE5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | BAG5 |
| Accession No. | Q9UL15 Q8CI32 Q5QJC9 |
| Alternate Names | BAG5; KIAA0873; BAG family molecular chaperone regulator 5; BAG-5; Bcl-2-associated athanogene 5 |
| Description | BCL2 associated athanogene 5(BAG5) Homo sapiens The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain, |
| Subcellular Localization | nucleus,mitochondrion,cytosol,membrane,inclusion body,perinuclear region of cytoplasm, |
| Protein Function | function:Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2.,similarity:Contains 4 BAG domains.,subunit:Binds to the ATPase domain of HSP70/HSC chaperones. Binds PARK2., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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