ITT5065
ITT5065
- Catalog: ITT5065
- Gene/Protein: POLE2
- Product Description: Immunotag™ DNA pol ε B Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DNA pol ε B |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human DNA pol ε B. |
| Specificity | DNA pol ε B Polyclonal Antibody detects endogenous levels of DNA pol ε B protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | POLE2 |
| Accession No. | P56282 O54956 |
| Alternate Names | POLE2; DPE2; DNA polymerase epsilon subunit 2; DNA polymerase II subunit 2; DNA polymerase epsilon subunit B |
| Description | catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,function:Participates in DNA repair and in chromosomal DNA replication.,miscellaneous:In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.,similarity:Belongs to the DNA polymerase epsilon subunit B family.,subunit:Consists of four subunits: POLE, POLE2, POLE3 and POLE4., |
| Cell Pathway/ Category | Purine metabolism,Pyrimidine metabolism,DNA replication,Base excision repair,Nucleotide excision repair, |
| Protein Expression | T cells, |
| Subcellular Localization | nucleoplasm,epsilon DNA polymerase complex,intracellular membrane-bounded organelle, |
| Protein Function | catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,function:Participates in DNA repair and in chromosomal DNA replication.,miscellaneous:In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.,similarity:Belongs to the DNA polymerase epsilon subunit B family.,subunit:Consists of four subunits: POLE, POLE2, POLE3 and POLE4., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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