ITT5068
ITT5068
- Catalog: ITT5068
- Gene/Protein: GABRE
- Product Description: Immunotag™ GABAA Rε Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | GABAA Rε |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human GABAA range: Rε. |
| Specificity | GABAA Rε Polyclonal Antibody detects endogenous levels of GABAA Rε protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GABRE |
| Accession No. | P78334 |
| Alternate Names | GABRE; Gamma-aminobutyric acid receptor subunit epsilon; GABA(A) receptor subunit epsilon |
| Description | gamma-aminobutyric acid type A receptor epsilon subunit(GABRE) Homo sapiens The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008], |
| Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
| Protein Expression | Brain, |
| Subcellular Localization | plasma membrane,integral component of membrane,cell junction,chloride channel complex,synapse,postsynaptic membrane,GABA-A receptor complex, |
| Protein Function | function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Generally pentameric. Associates with alpha and beta subunits.,tissue specificity:Expressed in many tissues. Highest levels of expression in adult heart and placenta., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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