ITT5077
ITT5077
- Catalog: ITT5077
- Gene/Protein: SV2C
- Product Description: Immunotag™ SV2C Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SV2C |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human SV2C. |
| Specificity | SV2C Polyclonal Antibody detects endogenous levels of SV2C protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SV2C |
| Accession No. | Q496J9 Q69ZS6 Q9Z2I6 |
| Alternate Names | SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C |
| Description | function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.,PTM:N-glycosylated.,similarity:Belongs to the major facilitator superfamily.,subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.,subunit:Interacts with SYT1 in a calcium-dependent manner., |
| Cell Pathway/ Category | ECM-receptor interaction, |
| Protein Expression | Brain, |
| Subcellular Localization | plasma membrane,synaptic vesicle,integral component of membrane,cell junction,synaptic vesicle membrane,neuron projection, |
| Protein Function | function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.,PTM:N-glycosylated.,similarity:Belongs to the major facilitator superfamily.,subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.,subunit:Interacts with SYT1 in a calcium-dependent manner., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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