ITT5082
ITT5082
- Catalog: ITT5082
- Gene/Protein: TRIM68
- Product Description: Immunotag™ SS-56 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SS-56 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human SS-56. |
| Specificity | SS-56 Polyclonal Antibody detects endogenous levels of SS-56 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TRIM68 |
| Accession No. | Q6AZZ1 Q8K243 |
| Alternate Names | TRIM68; GC109; RNF137; SS56; E3 ubiquitin-protein ligase TRIM68; RING finger protein 137; SSA protein SS-56; SS-56; Tripartite motif-containing protein 68 |
| Description | tripartite motif containing 68(TRIM68) Homo sapiens This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015], |
| Protein Expression | Brain, |
| Subcellular Localization | intracellular,nucleus,nucleolus,cytoplasm,Golgi apparatus,cytosol,perinuclear region of cytoplasm, |
| Protein Function | disease:Target of immune response in patients with systemic lupus erythematosus (SLE), primary Sjoegren syndrome or HIV-1 infection.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,tissue specificity:Detected in all tissues. High expression is noted in spleen and in fetal liver., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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