ITT5089
ITT5089
- Catalog: ITT5089
- Gene/Protein: IL28RA
- Product Description: Immunotag™ IL-28Rα Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | IL-28Rα |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human IL-28Rα. |
| Specificity | IL-28Rα Polyclonal Antibody detects endogenous levels of IL-28Rα protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | IL28RA |
| Accession No. | Q8IU57 Q8CGK5 |
| Alternate Names | IL28RA; IFNLR1; LICR2; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12;CRF2-12; Interferon lambda receptor 1; IFN-lambda receptor 1; IFN-lambda-R1; Likely interleukin or cytokine receptor 2; LICR2 |
| Description | interferon lambda receptor 1(IFNLR1) Homo sapiens The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Jak_STAT, |
| Protein Expression | PCR rescued clones,Pooled,Spleen, |
| Subcellular Localization | plasma membrane,integral component of membrane,interleukin-28 receptor complex, |
| Protein Function | function:The IL28RA/IL10RB dimer is a receptor for IL28A, IL28B and IL29. The ligand/receptor complex seems to signal through the Jak-STAT pathway.,similarity:Belongs to the type II cytokine receptor family.,similarity:Contains 1 fibronectin type-III domain.,subunit:Heterodimer with IL10RB.,tissue specificity:Widely expressed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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