ITT5102
ITT5102
- Catalog: ITT5102
- Gene/Protein: SLC6A14
- Product Description: Immunotag™ SLC6A14 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | SLC6A14 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the C-terminal region of human SLC6A14. |
| Specificity | SLC6A14 Polyclonal Antibody detects endogenous levels of SLC6A14 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SLC6A14 |
| Accession No. | Q9UN76 Q9JMA9 |
| Alternate Names | SLC6A14; Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+; Amino acid transporter ATB0+; Solute carrier family 6 member 14 |
| Description | solute carrier family 6 member 14(SLC6A14) Homo sapiens This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010], |
| Protein Expression | Mammary gland,Trachea, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane,brush border membrane,vesicle,extracellular exosome, |
| Protein Function | disease:Genetic variations in SLC6A14 may be associated with susceptibility to X-linked obesity (OBX) [MIM:300306]. Obesity has been shown to predispose to disorders such as type 2 diabetes, coronary heart disease, hypertension, osteoarthritis, and certain cancers. Common forms of obesity are most likely caused by multiple genetic and environmental factors, and their interactions.,function:Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner.,miscellaneous:Transport inhibited by BCH (2-aminobicyclo-[2.2.1]-heptane-2-carboxylic acid).,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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