ITT5149
ITT5149
- Catalog: ITT5149
- Gene/Protein: FAF1
- Product Description: Immunotag™ FAF1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FAF1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from FAF1, at AA range: 461-510 |
| Specificity | FAF1 Polyclonal Antibody detects endogenous levels of FAF1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | FAF1 |
| Accession No. | Q9UNN5 P54731 Q924K2 |
| Alternate Names | FAF1; UBXD12; UBXN3A; CGI-03; FAS-associated factor 1; hFAF1; UBX domain-containing protein 12; UBX domain-containing protein 3A |
| Description | Fas associated factor 1(FAF1) Homo sapiens Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Kidney,Liver,Testis, |
| Subcellular Localization | nucleus,nuclear envelope,cytosol,integral component of membrane,CD95 death-inducing signaling complex,VCP-NPL4-UFD1 AAA ATPase complex,perinuclear region of cytoplasm, |
| Protein Function | function:Potentiates but cannot initiate FAS-induced apoptosis.,similarity:Contains 1 UBX domain.,subunit:Specifically interacts with the cytoplasmic domain of FAS.,tissue specificity:Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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