ITT5162
ITT5162
- Catalog: ITT5162
- Gene/Protein: DNAJA1
- Product Description: Immunotag™ HSP40-4 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | HSP40-4 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from DnaJ homolog subfamily A member 1 at AA range: 71-120 |
| Specificity | HSP40-4 Polyclonal Antibody detects endogenous levels of HSP40-4 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DNAJA1 |
| Accession No. | P31689 P63037 P63036 |
| Alternate Names | DNAJA1; DNAJ2; HDJ2; HSJ2; HSPF4; DnaJ homolog subfamily A member 1; DnaJ protein homolog 2; HSDJ; Heat shock 40 kDa protein 4; Heat shock protein J2; HSJ-2; Human DnaJ protein 2; hDj-2 |
| Description | DnaJ heat shock protein family (Hsp40) member A1(DNAJA1) Homo sapiens This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes. [provided by RefSeq, Sep 2015], |
| Protein Expression | Amygdala,Epithelium,Placenta,Testes,Testis, |
| Subcellular Localization | ubiquitin ligase complex,nucleus,mitochondrion,cytosol,membrane,perinuclear region of cytoplasm,extracellular exosome,cytoplasmic side of endoplasmic reticulum membrane, |
| Protein Function | function:Co-chaperone of Hsc70. Seems to play a role in protein import into mitochondria.,similarity:Contains 1 CR-type zinc finger.,similarity:Contains 1 J domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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