ITT5178
ITT5178
- Catalog: ITT5178
- Gene/Protein: FGF20
- Product Description: Immunotag™ FGF-20 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | FGF-20 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from FGF-20, at AA range: C-TERM |
Specificity | FGF-20 Polyclonal Antibody detects endogenous levels of FGF-20 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | FGF20 |
Accession No. | Q9NP95 Q9ESL9 Q9EST9 |
Alternate Names | FGF20; Fibroblast growth factor 20; FGF-20 |
Description | fibroblast growth factor 20(FGF20) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009], |
Cell Pathway/ Category | MAPK_ERK_Growth,MAPK_G_Protein,Regulates Actin and Cytoskeleton,Pathways in cancer,Melanoma, |
Protein Expression | Brain,PCR rescued clones, |
Subcellular Localization | extracellular region,intracellular, |
Protein Function | function:Neurotrophic factor that regulates central nervous development and function.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Predominantly expressed in the cerebellum., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |