ITT5205
ITT5205
- Catalog: ITT5205
- Gene/Protein: CEACAM1/CEACAM5
- Product Description: Immunotag™ CEACAM1/5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | CEACAM1/5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human CEACAM1/CEACAM5. AA range:31-80 |
| Specificity | CEACAM1/5 Polyclonal Antibody detects endogenous levels of CEACAM1/5 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CEACAM1/CEACAM5 |
| Accession No. | P13688 P31809 |
| Alternate Names | CEACAM1; BGP; BGP1; Carcinoembryonic antigen-related cell adhesion molecule 1; Biliary glycoprotein 1; BGP-1; CD66a; CEACAM5; CEA; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e |
| Description | carcinoembryonic antigen related cell adhesion molecule 1(CEACAM1) Homo sapiens This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue thre |
| Protein Expression | Leukocyte,Liver,Plasma,Skin, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,cell-cell junction,adherens junction,basal plasma membrane,cell surface,membrane,integral component of membrane,apical plasma membrane,lateral plasma membra |
| Protein Function | disease:Increased serum levels of BGP-1 are found in individuals suffering from hepatic disorders.,disease:Loss or reduced expression is a major event in colorectal carcinogenesis.,similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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