ITT5209
ITT5209
- Catalog: ITT5209
- Gene/Protein: CALB1
- Product Description: Immunotag™ Calbindin D28K Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Calbindin D28K |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Calbindin D28K, at AA range: 181-230 |
| Specificity | Calbindin D28K Polyclonal Antibody detects endogenous levels of Calbindin D28K protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CALB1 |
| Accession No. | P05937 P12658 P07171 |
| Alternate Names | CALB1; CAB27; Calbindin; Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type |
| Description | calbindin 1(CALB1) Homo sapiens The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015], |
| Protein Expression | Brain,Cerebellum,Kidney,Lung,Substantia nigra, |
| Subcellular Localization | nucleus,cytosol,axon,dendrite,neuronal cell body,terminal bouton,synapse,extracellular exosome, |
| Protein Function | domain:This protein has four functional calcium-binding sites; potential sites II and VI have lost affinity for calcium.,function:Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.,online information:Calbindin entry,similarity:Belongs to the calbindin family.,similarity:Contains 5 EF-hand domains.,subunit:Interacts with RANBP9., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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