ITT5216
ITT5216
- Catalog: ITT5216
- Gene/Protein: SERPINA4
- Product Description: Immunotag™ Kallistatin Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | KalliSTATin |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA4. AA range:161-210 |
| Specificity | Kallistatin Polyclonal Antibody detects endogenous levels of Kallistatin protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | SERPINA4 |
| Accession No. | P29622 |
| Alternate Names | SERPINA4; KST; PI4; Kallistatin; Kallikrein inhibitor; Peptidase inhibitor 4; PI-4; Serpin A4 |
| Description | function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma., |
| Protein Expression | Colon,Fetal liver,Plasma, |
| Subcellular Localization | extracellular region,extracellular space,platelet dense granule lumen,extracellular exosome, |
| Protein Function | function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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