ITT5230
ITT5230
- Catalog: ITT5230
- Gene/Protein: NRP2
- Product Description: Immunotag™ Neuropilin-2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | NeuropIL-in-2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Neuropilin-2, at AA range: internal |
| Specificity | Neuropilin-2 Polyclonal Antibody detects endogenous levels of Neuropilin-2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | NRP2 |
| Accession No. | O60462 O35375 O35276 |
| Alternate Names | NRP2; VEGF165R2; Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2 |
| Description | neuropilin 2(NRP2) Homo sapiens This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Human endometrium carcinoma cell line,Liver,Mammary gland,Ovary,Prostate adenocarcino |
| Subcellular Localization | semaphorin receptor complex,extracellular region,plasma membrane,membrane,integral component of membrane,axon, |
| Protein Function | function:High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.,similarity:Belongs to the neuropilin family.,similarity:Contains 1 MAM domain.,similarity:Contains 2 CUB domains.,similarity:Contains 2 F5/8 type C domains.,subunit:Heterodimer with NRP1 (Probable). Binds PLXNB1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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