ITT5284
ITT5284
- Catalog: ITT5284
- Gene/Protein: RHAG
- Product Description: Immunotag™ CD241 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD241 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Ammonium transporter Rh type A at AA range: 1-50 |
| Specificity | CD241 Polyclonal Antibody detects endogenous levels of CD241 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | RHAG |
| Accession No. | Q02094 Q9QUT0 Q7TNK7 |
| Alternate Names | RHAG; RH50; Ammonium transporter Rh type A; Erythrocyte membrane glycoprotein Rh50; Erythrocyte plasma membrane 50 kDa glycoprotein; Rh50A; Rhesus blood group family type A glycoprotein;Rh family type A glycoprotein; Rh type A glycoprotein; Rhesus blood group-associated ammonia channel; Rhesus blood group-associated glycoprotein; CD241 |
| Description | Rh-associated glycoprotein(RHAG) Homo sapiens The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.[provided by RefSeq, Mar 2009], |
| Protein Expression | Bone marrow,Heart,Liver,Peripheral leukocytes, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,membrane,integral component of membrane, |
| Protein Function | disease:Defects in RHAG are the cause of regulator type Rh-null hemolytic anemia (RHN) [MIM:268150]; also called Rh-deficiency syndrome. RHN is a form of chronic hemolytic anemia in which the red blood cells have a stomatocytosis and spherocytosis morphology, an increased osmotic fragility, an altered ion transport system, and abnormal membrane phospholipid organization.,function:Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.,similarity:Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.,subunit:Heterotetramer.,tissue specificity:Erythrocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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