ITT5287
ITT5287
- Catalog: ITT5287
- Gene/Protein: PROCR
- Product Description: Immunotag™ CD201 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD201 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Endothelial protein C receptor at AA range: 141-190 |
| Specificity | CD201 Polyclonal Antibody detects endogenous levels of CD201 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PROCR |
| Accession No. | Q9UNN8 Q64695 Q4V8I1 |
| Alternate Names | PROCR; EPCR; Endothelial protein C receptor; Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD201 |
| Description | protein C receptor(PROCR) Homo sapiens The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013], |
| Protein Expression | Endothelial cell,Pancreas, |
| Subcellular Localization | extracellular region,centrosome,plasma membrane,integral component of plasma membrane,focal adhesion,cell surface,extracellular exosome, |
| Protein Function | function:Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.,PTM:A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.,PTM:N-glycosylated.,tissue specificity:Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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