ITT5298
ITT5298
- Catalog: ITT5298
- Gene/Protein: IL29
- Product Description: Immunotag™ IL-29 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | IL-29 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human IL29. AA range:121-170 |
Specificity | IL-29 Polyclonal Antibody detects endogenous levels of IL-29 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | IL29 |
Accession No. | Q8IU54 |
Alternate Names | IL29; IFNL1; ZCYTO21; Interleukin-29; IL-29; Cytokine Zcyto21; Interferon lambda-1; IFN-lambda-1 |
Description | interferon lambda 1(IFNL1) Homo sapiens This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Jak_STAT, |
Subcellular Localization | extracellular region,extracellular space,intracellular,interleukin-28 receptor complex, |
Protein Function | function:Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.,induction:By viral infections or double stranded RNA.,online information:Interleukin-29 entry,similarity:Belongs to the IL-28/IL-29 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |