ITT5324
ITT5324
- Catalog: ITT5324
- Gene/Protein: FOXA1/FOXA2/FOXA3
- Product Description: Immunotag™ HNF-3α/β/γ Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | HNF3α/β/γ |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human HNF-3α/β/γ around the non-acetylation site of K265 |
| Specificity | HNF-3α/β/γ Polyclonal Antibody detects endogenous levels of HNF-3α/β/γ protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | FOXA1/FOXA2/FOXA3 |
| Accession No. | P55317 P35582 P23512 |
| Alternate Names | FOXA1; HNF3A; TCF3A; Hepatocyte nuclear factor 3-alpha; HNF-3-alpha; HNF-3A; Forkhead box protein A1; Transcription factor 3A; TCF-3A; FOXA2; HNF3B; TCF3B; Hepatocyte nuclear factor 3-beta; HNF-3-beta; HNF-3B; Forkhead box protein A2;Transcription factor 3B; TCF-3B; FOXA3; HNF3G; TCF3G; Hepatocyte nuclear factor 3-gamma; HNF-3-gamma; HNF-3G; Fork head-related protein FKH H3; Forkhead box protein A3; Transcription factor 3G; TCF-3G |
| Description | forkhead box A1(FOXA1) Homo sapiens This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq, Jul 2008], |
| Protein Expression | Lung,Testis,Trachea, |
| Subcellular Localization | nucleus,nucleolus,microvillus, |
| Protein Function | function:Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes.,online information:Hepatocyte nuclear factors entry,similarity:Contains 1 fork-head DNA-binding domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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