ITT5480
ITT5480
- Catalog: ITT5480
- Gene/Protein: LAG3
- Product Description: Immunotag™ CD223 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CD223 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from Lymphocyte activation gene 3 protein at AA range: 91-140 |
Specificity | CD223 Polyclonal Antibody detects endogenous levels of CD223 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | LAG3 |
Accession No. | P18627 Q61790 Q5BK54 |
Alternate Names | LAG3; FDC; Lymphocyte activation gene 3 protein; LAG-3; Protein FDC; CD223 |
Description | lymphocyte activating 3(LAG3) Homo sapiens Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008], |
Protein Expression | Spleen, |
Subcellular Localization | external side of plasma membrane,integral component of membrane, |
Protein Function | function:Involved in lymphocyte activation. Binds to HLA class-II antigens.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:On cell surface of activated NK and T-lymphocytes., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |