ITT5516
ITT5516
- Catalog: ITT5516
- Gene/Protein: FLT3LG
- Product Description: Immunotag™ Flt3-L Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | FLT3-L |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human FLT3LG. AA range:171-220 |
| Specificity | Flt3-L Polyclonal Antibody detects endogenous levels of Flt3-L protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | FLT3LG |
| Accession No. | P49771 P49772 |
| Alternate Names | FLT3LG; Fms-related tyrosine kinase 3 ligand; Flt3 ligand; Flt3L; SL cytokine |
| Description | fms related tyrosine kinase 3 ligand(FLT3LG) Homo sapiens Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Hematopoietic cell lineage,Pathways in cancer, |
| Protein Expression | Brain,Spleen, |
| Subcellular Localization | extracellular region,extracellular space,membrane,integral component of membrane,intrinsic component of external side of plasma membrane, |
| Protein Function | function:Stimulates the proliferation of early hematopoietic cells. Synergizes well with a number of other colony stimulating factors and interleukins.,subunit:Homodimer (isoform 2)., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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