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ITT5552

ITT5552
ITT5552
ITT5552
  • Catalog: ITT5552
  • Gene/Protein: FGF4
  • Product Description: Immunotag™ FGF-4 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ FGF-4 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein FGF-4
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from the C-terminal region of human FGF4. AA range:151-200
Specificity FGF-4 Polyclonal Antibody detects endogenous levels of FGF-4 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name FGF4
Accession No. P08620 P11403
Alternate Names FGF4; HST; HSTF1; KS3; Fibroblast growth factor 4; FGF-4; Heparin secretory-transforming protein 1; HST; HST-1; HSTF-1; Heparin-binding growth factor 4; HBGF-4; Transforming protein KS3
Description fibroblast growth factor 4(FGF4) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category MAPK_ERK_Growth,MAPK_G_Protein,Regulates Actin and Cytoskeleton,Pathways in cancer,Melanoma,
Subcellular Localization extracellular region,intracellular,
Protein Function function:Can transform NIH 3T3 cells from a human stomach tumor (hst) and from karposi's sarcoma (KS3). It has a mitogenic activity.,similarity:Belongs to the heparin-binding growth factors family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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