ITT5562
ITT5562
- Catalog: ITT5562
- Gene/Protein: DKK1
- Product Description: Immunotag™ Dkk-1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DKK-1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human DKK1. AA range:181-230 |
| Specificity | Dkk-1 Polyclonal Antibody detects endogenous levels of Dkk-1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | DKK1 |
| Accession No. | O94907 O54908 |
| Alternate Names | DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK |
| Description | dickkopf WNT signaling pathway inhibitor 1(DKK1) Homo sapiens This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | WNT,WNT-T CELL |
| Protein Expression | Brain,Fetal kidney,Leiomyosarcoma, |
| Subcellular Localization | extracellular region,extracellular space,plasma membrane,early endosome membrane, |
| Protein Function | function:Inhibitor of Wnt signaling pathway.,similarity:Belongs to the dickkopf family.,tissue specificity:Placenta., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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