ITT5607
ITT5607
- Catalog: ITT5607
- Gene/Protein: TNFRSF4
- Product Description: Immunotag™ Ox40 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Ox40 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human TNFRSF4. AA range:131-180 |
| Specificity | Ox40 Polyclonal Antibody detects endogenous levels of Ox40 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TNFRSF4 |
| Accession No. | P43489 P47741 |
| Alternate Names | TNFRSF4; TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD134 |
| Description | TNF receptor superfamily member 4(TNFRSF4) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction, |
| Protein Expression | Brain, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,cell surface, |
| Protein Function | function:Receptor for TNFSF4/OX40L/GP34.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Interacts with TRAF2, TRAF3 and TRAF5., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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