ITT5620
ITT5620
- Catalog: ITT5620
- Gene/Protein: TNFSF4
- Product Description: Immunotag™ Ox40L Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Ox40L |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human TNFSF4. AA range:31-80 |
| Specificity | Ox40L Polyclonal Antibody detects endogenous levels of Ox40L protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | TNFSF4 |
| Accession No. | P23510 P43488 Q9Z2P3 |
| Alternate Names | TNFSF4; TXGP1; Tumor necrosis factor ligand superfamily member 4; Glycoprotein Gp34; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; CD252 |
| Description | tumor necrosis factor superfamily member 4(TNFSF4) Homo sapiens This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction, |
| Protein Expression | Testis, |
| Subcellular Localization | extracellular space,plasma membrane,integral component of plasma membrane,cell surface,integral component of membrane, |
| Protein Function | disease:Genetic variation in TNFSF4 influences susceptibility to systemic lupus erythematosus (SLE) [MIM:152700]. SLE is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.,function:Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.,induction:By human T-cell leukemia virus type I transactivator P40-TAX.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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