ITT5638
ITT5638
- Catalog: ITT5638
- Gene/Protein: GYPA
- Product Description: Immunotag™ CD235a Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD235a |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human GYPA. AA range:41-90 |
| Specificity | CD235a Polyclonal Antibody detects endogenous levels of CD235a protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | GYPA |
| Accession No. | P02724 P14220 |
| Alternate Names | GYPA; GPA; Glycophorin-A; MN sialoglycoprotein; PAS-2; Sialoglycoprotein alpha; CD235a |
| Description | glycophorin A (MNS blood group)(GYPA) Homo sapiens Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Hematopoietic cell lineage, |
| Protein Expression | Blood,Bone marrow,Kidney,Liver,Lung,Miltenberger class V, |
| Subcellular Localization | plasma membrane,membrane,integral component of membrane,extracellular exosome, |
| Protein Function | function:Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors and also binds influenza virus.,online information:Blood group antigen gene mutation database,polymorphism:Along with GYPB, GYPA is responsible for the MNS blood group system.,similarity:Belongs to the glycophorin A family., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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