ITT5643
ITT5643
- Catalog: ITT5643
- Gene/Protein: AIMP1
- Product Description: Immunotag™ EMAP II Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | EMAP- II |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human AIMP1. AA range:91-140 |
| Specificity | EMAP II Polyclonal Antibody detects endogenous levels of EMAP II protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | AIMP1 |
| Accession No. | Q12904 P31230 |
| Alternate Names | AIMP1; EMAP2; SCYE1; Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; Multisynthase complex auxiliary component p43 |
| Description | aminoacyl tRNA synthetase complex interacting multifunctional protein 1(AIMP1) Homo sapiens The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008], |
| Protein Expression | Trachea, |
| Subcellular Localization | extracellular space,nucleus,cytoplasm,endoplasmic reticulum,Golgi apparatus,cytosol,cell surface,membrane,aminoacyl-tRNA synthetase multienzyme complex,methionyl glutamyl tRNA synthetase complex, |
| Protein Function | angiogenesis, blood vessel development, regulation of endothelial cell proliferation, negative regulation of endothelial cell proliferation, vasculature development, monosaccharide metabolic process, glucose metabolic process, tRNA metabolic process, translation, tRNA aminoacylation for protein translation, apoptosis, cell motion, chemotaxis,defense response, inflammatory response, cell adhesion, cell-cell signaling, behavior, locomotory behavior, cell death,negative regulation of cell proliferation, response to wounding, programmed cell death, death, cell migration, hexose metabolic process, biological adhesion, ncRNA metabolic process, regulation of cell proliferation, taxis, amino acid activation, tRNA aminoacylation, blood vessel morphogenesis, cell motility, leukocyte migration, localization of cell, |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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