ITT5674
ITT5674
- Catalog: ITT5674
- Gene/Protein: APPBP2
- Product Description: Immunotag™ APP-BP2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | APP-BP2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from APP-BP2, at AA range: 390-470 |
| Specificity | APP-BP2 Polyclonal Antibody detects endogenous levels of APP-BP2 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | APPBP2 |
| Accession No. | Q92624 Q9DAX9 A5HK05 |
| Alternate Names | APPBP2; KIAA0228; PAT1; Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1 |
| Description | amyloid beta precursor protein binding protein 2(APPBP2) Homo sapiens The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], |
| Protein Expression | Bone marrow,Cervix carcinoma,Skin, |
| Subcellular Localization | nucleus,cytoplasm,microtubule,microtubule associated complex,cytoplasmic vesicle membrane, |
| Protein Function | function:May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.,PTM:Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.,similarity:Contains 8 TPR repeats.,subcellular location:Associated with membranes and microtubules.,subunit:Binds APP., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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