ITT5683
ITT5683
- Catalog: ITT5683
- Gene/Protein: PIK3C2G
- Product Description: Immunotag™ PI 3-Kinase C2γ Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PI 3-Kinase C2γ |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the N-terminal region of human PI 3-Kinase C2γ. |
| Specificity | PI 3-Kinase C2γ Polyclonal Antibody detects endogenous levels of PI 3-Kinase C2γ protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | PIK3C2G |
| Accession No. | O75747 O70167 |
| Alternate Names | PIK3C2G; Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PtdIns-3-kinase C2 subunit gamma; Phosphoinositide 3-kinase-C2-gamma |
| Description | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma(PIK3C2G) Homo sapiens The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014], |
| Cell Pathway/ Category | Inositol phosphate metabolism,Phosphatidylinositol signaling system, |
| Protein Expression | Epithelium,Liver,Mammary gl |
| Subcellular Localization | intracellular,cytosol,plasma membrane,phosphatidylinositol 3-kinase complex, |
| Protein Function | catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate.,function:In vitro, phosphorylates PtdIns and PtdIns4P but not PtdIns(4,5)P2.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI3K/PI4K domain.,similarity:Contains 1 PX (phox homology) domain.,tissue specificity:Highly expressed in liver, prostate and testis. Lower levels in small intestine, kidney and pancreas., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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