Datasheet |
|
Target Protein |
HSP9000 |
Clonality |
Polyclonal |
Storage/Stability |
-20°C/1 year |
Application |
WB,ELISA |
Recommended Dilution |
WB 1:500-2000, ELISA 1:10000-20000 |
Concentration |
1 mg/ml |
Reactive Species |
Human,Mouse,Rat |
Host Species |
Rabbit |
Immunogen |
Synthetic Peptide of HSP 90 |
Specificity |
HSP 90 Polyclonal Antibody detects endogenous levels of HSP 90 |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name |
HSP90AA1 HSP90A HSPC1 HSPCA |
Accession No. |
P07900 P07901 P82995 |
Alternate Names |
heat shock protein 90kDa alpha (cytosolic), class A member 2; heat shock protein 90kDa alpha (cytosolic), class A member 1 |
Description |
heat shock protein 90 alpha family class A member 1(HSP90AA1) Homo sapiens The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012], |
Cell Pathway/ Category |
Antigen processing and presentation,NOD-like receptor,Progesterone-mediated oocyte maturation,Pathways in cancer,Prostate cancer, |
Protein Expression |
Adult brain,Brain,Brain cortex,Breast,Cajal-Retzius |
Subcellular Localization |
extracellular region,nucleus,nucleoplasm,cytoplasm,cytosol,plasma membrane,cell surface,membrane,basolateral plasma membrane,apical plasma membrane,extracellular matrix,brush border membrane, |
Protein Function |
caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,function:Molecular chaperone.,function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1., |
Usage |
For Research Use Only! Not for diagnostic or therapeutic procedures. |