ITT5757
ITT5757
- Catalog: ITT5757
- Gene/Protein: RHEB RHEB2
- Product Description: Immunotag™ RHEB Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RHEB |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat,Predicted:Cow |
| Host Species | Rabbit |
| Immunogen | Synthetic Peptide of RHEB |
| Specificity | RHEB Polyclonal Antibody detects endogenous levels of RHEB |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | RHEB RHEB2 |
| Accession No. | Q15382 Q921J2 Q62639 |
| Alternate Names | Ras homolog enriched in brain |
| Description | Ras homolog enriched in brain(RHEB) Homo sapiens This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | mTOR,Insulin_Receptor, |
| Protein Expression | Brain,Mammary carcinoma,Muscle,Psoriatic skin,Skin,Testis, |
| Subcellular Localization | Golgi membrane,intracellular,spliceosomal complex,lysosomal membrane,endoplasmic reticulum membrane,cytosol,membrane,extracellular exosome, |
| Protein Function | function:Not known; binds GTP and exhibits intrinsic GTPase activity.,similarity:Belongs to the small GTPase superfamily. Rheb family.,tissue specificity:Ubiquitous. Highest levels observed in skeletal and cardiac muscle., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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