ITT5817
ITT5817
- Catalog: ITT5817
- Gene/Protein: CDX2 CDX3
- Product Description: Immunotag™ Cdx2 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CDX2 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat |
Host Species | Rabbit |
Immunogen | Synthetic peptide from human protein at AA range: 201-250 |
Specificity | The antibody detects endogenous Cdx2 protein |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CDX2 CDX3 |
Accession No. | Q99626 P43241 |
Alternate Names | CDX2 CDX3 |
Description | caudal type homeobox 2(CDX2) Homo sapiens This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012], |
Protein Expression | Colon,Colon carcinoma, |
Subcellular Localization | condensed nuclear chromosome,nucleus,nucleoplasm,transcriptional repressor complex,protein complex, |
Protein Function | function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |