ITT5836
ITT5836
- Catalog: ITT5836
- Gene/Protein: IRS2
- Product Description: Immunotag™ IRS2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | IRS-2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 660-700 |
| Specificity | The antibody detects endogenous IRS2 protein |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | IRS2 |
| Accession No. | Q9Y4H2 P81122 |
| Alternate Names | IRS2 |
| Description | insulin receptor substrate 2(IRS2) Homo sapiens This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Neurotrophin,Insulin_Receptor,Adipocytokine,Type II diabetes mellitus,Aldosterone-regulated sodium reabsorption, |
| Protein Expression | Blood,Epithelium,Platelet, |
| Subcellular Localization | cytosol,plasma membrane, |
| Protein Function | function:May mediate the control of various cellular processes by insulin.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IRS-type PTB domain.,similarity:Contains 1 PH domain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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