ITT5847
ITT5847
- Catalog: ITT5847
- Gene/Protein: ST6GAL1 SIAT1
- Product Description: Immunotag™ ST6GAL1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ST6GAL1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 63-135 |
| Specificity | The antibody detects endogenous ST6GAL1 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ST6GAL1 SIAT1 |
| Accession No. | P15907 Q64685 P13721 |
| Alternate Names | Beta-galactoside alpha-2,6-sialyltransferase 1 (Alpha 2,6-ST 1) (EC 2.4.99.1) (B-cell antigen CD75) (CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1) (ST6Gal I) (ST6GalI) (Sialyltransferase 1) |
| Description | ST6 beta-galactoside alpha-2,6-sialyltransferase 1(ST6GAL1) Homo sapiens This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009], |
| Cell Pathway/ Category | N-Glycan biosynthesis, |
| Protein Expression | Liver,Lymph,Placenta,Skin,Spleen,Thymus, |
| Subcellular Localization | Golgi membrane,Golgi apparatus,integral component of membrane,integral component of Golgi membrane,Golgi cisterna membrane,extracellular exosome, |
| Protein Function | catalytic activity:CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine.,function:Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.,online information:GlycoGene database,online information:ST6Gal I,pathway:Protein modification; protein glycosylation.,PTM:The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the glycosyltransferase 29 family.,subcellular location:Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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