ITT5883
ITT5883
- Catalog: ITT5883
- Gene/Protein: LGALS3BP M2BP
- Product Description: Immunotag™ Mac-2BP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | M2BP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 100-160 |
| Specificity | The antibody detects endogenous Mac-2BP |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | LGALS3BP M2BP |
| Accession No. | Q08380 Q07797 |
| Alternate Names | Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K) |
| Description | galectin 3 binding protein(LGALS3BP) Homo sapiens The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008], |
| Protein Expression | Ascites,Bile,Colon,Fibroblast,Liver,Lung,Milk,Plasma,Saliva,Serum, |
| Subcellular Localization | extracellular region,proteinaceous extracellular matrix,extracellular space,membrane,extracellular matrix,platelet dense granule lumen,extracellular exosome,blood microparticle, |
| Protein Function | function:Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.,similarity:Contains 1 BACK (BTB/Kelch associated) domain.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 SRCR domain.,subunit:Homodimers and homomultimers. The multimers form ring-like structures with a diameter of 30-40 nm. Binds LGALS1 and LGALS3. Binds ITGB1, COL4A1, COL5A1, COL6A1, FN1 and NID.,tissue specificity:Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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