ITT5889
ITT5889
- Catalog: ITT5889
- Gene/Protein: FCGR1A FCG1 FCGR1 IGFR1
- Product Description: Immunotag™ CD64 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD64 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 230-280 |
| Specificity | The antibody detects endogenous CD64 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | FCGR1A FCG1 FCGR1 IGFR1 |
| Accession No. | P12314 P26151 |
| Alternate Names | High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64) |
| Description | Fc fragment of IgG receptor Ia(FCGR1A) Homo sapiens This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Hematopoietic cell lineage,Fc gamma R-mediated phagocytosis,Systemic lupus erythematosus, |
| Protein Expression | Blood,Liver,Lung, |
| Subcellular Localization | plasma membrane,integral component of membrane,clathrin-coated endocytic vesicle membrane,early endosome membrane, |
| Protein Function | function:High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.,online information:FCGR1A mutation db,PTM:N-glycosylated.,PTM:Phosphorylated on serine residues.,similarity:Belongs to the immunoglobulin superfamily. FCGR1 family.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Stabilized at the cell membrane through interaction with FCER1G.,subunit:Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL.,tissue specificity:Monocyte/macrophage specific., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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