ITT5891
ITT5891
- Catalog: ITT5891
- Gene/Protein: LAMP3 DCLAMP TSC403
- Product Description: Immunotag™ DC-LAMP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | DC-LAMP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide from human protein at AA range: 261-310 |
| Specificity | The antibody detects endogenous DC-LAMP |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | LAMP3 DCLAMP TSC403 |
| Accession No. | Q9UQV4 Q7TST5 |
| Alternate Names | Lysosome-associated membrane glycoprotein 3 (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD antigen CD208) |
| Description | lysosomal associated membrane protein 3(LAMP3) Homo sapiens Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010], |
| Cell Pathway/ Category | Lysosome, |
| Protein Expression | Lung,Testis, |
| Subcellular Localization | lysosomal membrane,early endosome,plasma membrane,membrane,integral component of membrane,vesicle,perinuclear region of cytoplasm,alveolar lamellar body membrane, |
| Protein Function | function:Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells.,similarity:Belongs to the LAMP family.,tissue specificity:Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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